21-Deoxy Cortisone

CAS : 1882-82-2

Ref. TM-TN8231

Informations sur le produit

• Nom: 21-Deoxy Cortisone
• Synonymes: 21-Desoxycortisone, 17-Alpha-Hydroxypregn-4-Ene-3,11,20-Trione, 17-Hydroxypregn-4-Ene-3,11,20-Trione, 17α-Hydroxy-11-oxoprogesterone, 17α-Hydroxypregn-4-ene-3,11,20-trione, 21-Deoxycortisone, 4-Pregnene-17α-ol-3,11,20-trione, 6-Pregn-4-en-17α-ol-3,11,20-trione, NSC 38722, Pregn-4-ene-3,11,20-trione, 17-hydroxy-

Description

21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.

• Marque: Targetmol

Propriétés chimiques

• Masse moléculaire: 344.44
• Formule: C₂₁H₂₈O₄