Acarbose-1-phenylthiol Dodeca(p-methoxybenzyl Ether)

Ref. TR-A123510

Informations sur le produit

• Nom: Acarbose-1-phenylthiol Dodeca(p-methoxybenzyl Ether)
• Synonymes: (2R,3R,4S,5R,6R)-6-(((2R,3R,4S,5R,6R)-6-(((2R,3R,4S,5R,6S)-4,5-bis((4-Methoxybenzyl)oxy)-2-(((4-methoxybenzyl)oxy)methyl)-6-(phenylthio)tetrahydro-2H-pyran-3-yl)oxy)-4,5-bis((4-methoxybenzyl)oxy)-2-(((4-methoxybenzyl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)-4,5-bis((4-methoxybenzyl)oxy)-2-methyl-N-((1S,4S,5S,6S)-4,5,6-tris((4-methoxybenzyl)oxy)-3-(((4-methoxybenzyl)oxy)methyl)cyclohex-2-en-1-yl)tetrahydro-2H-pyran-3-amine

Description

Applications Acarbose-1-phenylthiol Dodeca(p-methoxybenzyl Ether) is an intermediate formed in the synthesis of α-D-Glucosyl Acarbose Impurity, a homolog of Acarbose (A123500) for use in the treatment of chronic diseases such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites (1,2,3). Acarbose impurity F.
References (1) Henrissal, B.: Biochem. J., 280, 309 (1991) (2) Qian, M., et al.: J. Mol. Biol., 231, 785 (1993) (3) Brzozowski, A., et al.: Biochemistry, 36, 10837 (1997)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 2179.55
• Formule: C₁₂₇H₁₄₃NO₂₉S
• Couleur/Forme: Neat
• SMILES: COc1ccc(COCC2=C[C@H](N[C@H]3C(OCc4ccc(OC)cc4)C(OCc4ccc(OC)cc4)[C@@H](O[C@@H]4C(COCc5ccc(OC)cc5)O[C@H](O[C@@H]5C(COCc6ccc(OC)cc6)O[C@@H](Sc6ccccc6)C(OCc6ccc(OC)cc6)C5OCc5ccc(OC)cc5)C(OCc5ccc(OC)cc5)C4OCc4ccc(OC)cc4)O[C@@H]3C)[C@H](OCc3ccc(OC)cc3)[C@@H](OCc3ccc(OC)cc3)[C@H]2OCc2ccc(OC)cc2)cc1