1-'[[2'-'(Aminocarbonyl)'[1,'1'-'biphenyl]'-'4-'yl]'methyl]'-'2-'ethoxy-1H-'benzimidazole-'7-'carbox

CAS : 147404-76-0

Ref. TR-A147405

Informations sur le produit

• Nom: 1-'[[2'-'(Aminocarbonyl)'[1,'1'-'biphenyl]'-'4-'yl]'methyl]'-'2-'ethoxy-1H-'benzimidazole-'7-'carbox
• Synonymes: 1-?[[2'-?(Aminocarbonyl)?[1,?1'-?biphenyl]?-?4-?yl]?methyl]?-?2-?ethoxy-1H-?benzimidazole-?7-?carboxylic Acid Methyl Ester, Azilsartan impurity A

Description

Applications 1-​[[2'-​(Aminocarbonyl)​[1,​1'-​biphenyl]​-​4-​yl]​methyl]​-​2-​ethoxy-1H-​benzimidazole-​7-​carboxylic Acid Methyl Ester is an intermediate in the synthesis of Degadant-3 (D229206), which is an intermediate used in the preparation of azilsartan kamedoxomil for use as an angiotensin II receptor blocker. Azilsartan Impurity.
References Garaga, S., et al.: Org. Process Res. Dev., 19, 514 (2015); Sethi, M. K., et al.: Pharma Chemica, 7, 20 (2015)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 429.47
• Formule: C₂₅H₂₃N₃O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C25H23N3O4/c1-3-32-25-27-21-10-6-9-20(24(30)31-2)22(21)28(25)15-16-11-13-17(14-12-16)18-7-4-5-8-19(18)23(26)29/h4-14H,3,15H2,1-2H3,(H2,26,29)
• Code InChI: InChIKey=HNNRUQRZSQWNFG-UHFFFAOYSA-N
• SMILES: CCOc1nc2cccc(C(=O)OC)c2n1Cc1ccc(-c2ccccc2C(N)=O)cc1