2-Acetyl Phenothiazine

CAS : 6631-94-3

Ref. TR-A187570

Informations sur le produit

• Nom: 2-Acetyl Phenothiazine
• Synonymes: ML 171, 1-(10H-Phenothiazin-2-yl)ethanone, Methyl Phenothiazin-2-yl Ketone, 2-Acetyl-10H-phenothiazine, 2-Acetylphenothiazine, NSC 169669, NSC 57951, 1-(10H-Phenothiazin-2-yl)ethan-1-one, 1-(10H-phenothiazin-2-yl)ethanone, Ethanone, 1-(10H-phenothiazin-2-yl)-, Ketone, methyl phenothiazin-2-yl, Labotest-Bb Lt00012652, Methyl Phenothiazin-2-Yl Ketone
• CAS: 6631-94-3

Description

Applications 2-Acetylphenothiazine is a potent and selective NADPH oxidase 1 (NOX1) inhibitor that blocks NOX1-dependent ROS generation. 2-Acetylphenothiazine has been shown to inhibit SrcYF-induced invadopodia formation in human DLD1 colon cancer cells.
References Gianni, D. et al.: ACS Chem. Biol., 5, 981 (2010); Azuine, M.A. et al.: Pharmacol. Res., 49, 161 (2004);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 241.31
• Formule: C₁₄H₁₁NOS
• Couleur/Forme: Neat
• InChI: InChI=1S/C14H11NOS/c1-9(16)10-6-7-14-12(8-10)15-11-4-2-3-5-13(11)17-14/h2-8,15H,1H3
• Code InChI: InChIKey=JWGBOHJGWOPYCL-UHFFFAOYSA-N
• SMILES: CC(=O)c1ccc2c(c1)Nc1ccccc1S2