Acyclovir Monophosphate

CAS : 66341-16-0

Ref. TR-A192500

Informations sur le produit

• Nom: Acyclovir Monophosphate
• Synonymes: 2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl dihydrogen phosphate, 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one phosphate (1:1), 6H-purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-, phosphate (1:1) (salt), Acycloguanosine monophosphate, 2-amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one phosphate (salt)

Description

Stability Hygroscopic
Applications A nucleoside analog phosphates for topical use in the treatment of herpes virus infections. A topical treatment that seems to bypass a key mechanism responsible for resistance to Acyclovir.
References Furman, P., et al.: J. Virol., 32, 72 (1979), Darby, G., et al.: J. Gen. Virol., 48, 451 (1980),Prisbe, E., et al.: J. Med. Chem., 29, 671 (1986), Ellis, M., et al.: Antimicrob. Agents Chemother., 33, 304 (1989),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 305.18
• Formule: C₈H₁₂N₅O₆P
• Couleur/Forme: Off-White
• InChI: InChI=1S/C8H12N5O6P/c9-8-11-6-5(7(14)12-8)10-3-13(6)4-18-1-2-19-20(15,16)17/h3H,1-2,4H2,(H2,15,16,17)(H3,9,11,12,14)
• Code InChI: InChIKey=KUOAJOVOKFATQE-UHFFFAOYSA-N
• SMILES: N=c1nc(O)c2ncn(COCCOP(=O)(O)O)c2[nH]1