Almotriptan Malate

CAS : 181183-52-8

Ref. TR-A575200

Informations sur le produit

• Nom: Almotriptan Malate
• Synonymes: LAS-31416 Malate,Butanedioic acid, 2-hydroxy-, compd. with N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-indole-3-ethanamine (1:1), Butanedioic acid, hydroxy-, compd. with 1-[[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine (1:1) (9CI), Pyrrolidine, 1-[[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]-, hydroxybutanedioate (1:1) (9CI), Almotrip forte, Axert, LAS 31416 D,L-malate acid, PNU 180638, PNU 180638E,, 1-[[3-(2-Dimethylaminoethyl)-5-Indolyl]Methanesulphonyl]Pyrrolidine Malate, 1-[[[2-(Dimethyl-Amino)Ethyl]-1H-Indol-5-Yl]Methyl]Sulfonyl]Pyrrolidine Malate, 2-hydroxybutanedioic acid - N,N-dimethyl-2-{5-[(pyrrolidin-1-ylsulfonyl)methyl]-1H-indol-3-yl}ethanamine (1:1), Almotriptan Maleate, Almotriptanmaleate, Butanedioic acid, 2-hydroxy-, compd. with N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-indole-3-ethanamine (1:1), Butanedioic acid, hydroxy-, compd with 1-[[[3-[2-(dimethylamino)ethyl]-1h-indol-5-yl]methyl]sulfonyl]pyrrolidine, Butanedioic acid, hydroxy-, compd. with 1-[[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine (1:1), LAS 31416 <span class="text-smallcaps">D</smallcap>,<smallcap>L</span>-malate acid, Las-31416 Malate, N,N-dimethyl-2-{5-[(pyrrolidin-1-ylsulfonyl)methyl]-1H-indol-3-yl}ethanamine, Pnu 180638, Pnu 180638E, Pyrrolidine, 1-[[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]-, hydroxybutanedioate (1:1)

Description

Applications Almotriptan is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.
References Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 469.55
• Formule: C₁₇H₂₅N₃O₂S·C₄H₆O₅
• Couleur/Forme: Neat
• InChI: 2,5H,1H2,(H,6,7)(H,8,9), InChI=1S/C17H25N3O2S.C4H6O5/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20, 5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3
• Code InChI: InChIKey=QHATUKWEVNMHRY-UHFFFAOYSA-N
• SMILES: CN(C)CCc1c[nH]c2ccc(CS(=O)(=O)N3CCCC3)cc12.O=C(O)CC(O)C(=O)O