AM 251

CAS : 183232-66-8

Ref. TR-A575805

Informations sur le produit

• Nom: AM 251
• Synonymes: 1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-, 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide, AM 251 (pharmaceutical), 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide, 1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-, Am 251, N-(Piperidin-1-Yl)-5-(4-Iodophenyl)-1-(2,4-Dichlorophenyl)-4-Methyl-1H-Pyrazole-3-Carboxamide

Description

Applications AM-251 is a biarylpyrazole compound that acts as an inverse CB1 cannabinoid receptor agonist and a selective GPR55 agonist.
References Kesser, C., et al.: Mol. Cell. Endocrinol., 302, 108 (2009), Araujo, J., et al.: Pharmacol., 83, 170 (2009), Malysz, J., et al.: Eur. J. Pharmacol., 603, 12 (2009),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 555.24
• Formule: C₂₂H₂₁Cl₂IN₄O
• Couleur/Forme: Neat
• InChI: InChI=1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
• Code InChI: InChIKey=BUZAJRPLUGXRAB-UHFFFAOYSA-N
• SMILES: Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(I)cc1