AM-1220

CAS : 137642-54-7

Ref. TR-A575835

Informations sur le produit

• Nom: AM-1220
• Synonymes: 1-[(1-Methylpiperidin-2-yl)methyl]-3-(1-naphthoyl)-indole, Methanone, [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-1-naphthalenyl-, [1-[(1-Methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-1-naphthalenylmethanone, {1-[(1-Methylpiperidin-2-yl)methyl]-1H-indol-3-yl}(naphthalin-1-yl)methanone, AM 1220, Methanone, [1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-1-naphthalenyl-

Description

Applications AM-1220 is a synthetic cannabimimetic indole derivative. AM-1220 acts as a potent and moderately selective agonist for the cannabinoid receptor CB1 with around 19 times the selectivity for CB1 over CB2 receptor. Synthetic cannabinoids
References Jarbe, T.U.C. et al.: Psychopharmacology, 216, 355 (2011); D'Ambra, T.E. et al.: Bioorg. Med. Chem. Lett., 6, 17 (1996);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 382.50
• Formule: C₂₆H₂₆N₂O
• Couleur/Forme: Neat
• InChI: InChI=1S/C26H26N2O/c1-27-16-7-6-11-20(27)17-28-18-24(22-13-4-5-15-25(22)28)26(29)23-14-8-10-19-9-2-3-12-21(19)23/h2-5,8-10,12-15,18,20H,6-7,11,16-17H2,1H3
• Code InChI: InChIKey=YWUVGTHIUYVNKV-ATUSAISYSA-N
• SMILES: CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)/C(=N\OC(C)(C)C(=O)OC(C)(C)C)c3csc(N)n3)[C@@H]2SC1