7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-oxo-heptanoic Acid

CAS : 1174657-07-8

Ref. TR-A604430

Informations sur le produit

• Nom: 7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-oxo-heptanoic Acid
• Synonymes: Cilastatin Impurity E

Description

Applications 7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-oxo-heptanoic Acid is an impurity of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 263.311
• Formule: C₁₀H₁₇NO₅S
• Couleur/Forme: Neat
• InChI: InChI=1S/C10H17NO5S/c11-7(9(13)14)6-17-5-3-1-2-4-8(12)10(15)16/h7H,1-6,11H2,(H,13,14)(H,15,16)/t7-/m0/s1
• Code InChI: InChIKey=HXXAUIXTYRHFNO-UHFFFAOYSA-N
• SMILES: CNC(=O)c1ccccn1