4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone

CAS : 2230479-30-6

Ref. TR-A609535

Informations sur le produit

• Nom: 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone
• Synonymes: Capecitabine Impurity

Description

Applications 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone is an impurity of Capecitabine (C175650), which is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).
References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 329.28
• Formule: C₁₃H₁₆FN₃O₆
• Couleur/Forme: Off White Powder
• InChI: InChI=1S/C13H16FN3O6/c1-5-9(22-6(2)18)10(23-7(3)19)12(21-5)17-4-8(14)11(15)16-13(17)20/h4-5,9-10,12H,1-3H3,(H2,15,16,20)/t5-,9-,10-,12+/m1/s1
• Code InChI: InChIKey=FWHJBYXBRSYWNM-BEISELTPSA-N
• SMILES: CCN(C)c1ccc(O)c2c1C[C@@H]1C[C@@H]3[C@@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@]3(O)C(O)=C1C2=O.Cl