4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid

CAS : 936890-98-1

Ref. TR-A611910

Informations sur le produit

• Nom: 4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid
• Synonymes: trans-4-[4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexanecarboxylic Acid, OSI 027
• CAS: 936890-98-1

Description

Applications This compound is a kinase inhibitor with anti-tumor activity, used in treatment of breast cancer. Dual mTORC1/C2 inhibitor.
References Li, H. et al.: Breast Canc. Res. Treat., 134, 1057 (2012);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 406.44
• Formule: C₂₁H₂₂N₆O₃
• Couleur/Forme: Pale Beige to Light Beige Solid
• InChI: InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4,9-12,25H,5-8H2,1H3,(H,28,29)(H2,22,23,24)/t11-,12-
• Code InChI: InChIKey=JROFGZPOBKIAEW-HAQNSBGRSA-N
• SMILES: COc1cccc2cc(-c3nc([C@H]4CC[C@H](C(=O)O)CC4)n4ncnc(N)c34)[nH]c12