(1S,2S,3R,5S)-3-Amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol Hydrochloride

Ref. TR-A612165

Informations sur le produit

• Nom: (1S,2S,3R,5S)-3-Amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol Hydrochloride
• Synonymes: (1S,2S,3R,5S)-3-Amino-5-(2-hydroxyethoxy)-1,2-cyclopentanediol Hydrochloride
• Marque: TRC
• Description: Applications (1S,2S,3R,5S)-3-Amino-5-(2-hydroxyethoxy)cyclopentane-1,2-diol Hydrochloride is used in the synthesis of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).References Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)

Propriétés chimiques

• Masse moléculaire: 213.659
• Formule: C₇H₁₅NO₄·HCl
• Couleur/Forme: Neat
• InChI: InChI=1S/C7H15NO4.ClH/c8-4-3-5(12-2-1-9)7(11)6(4)10;/h4-7,9-11H,1-3,8H2;1H/t4-,5+,6+,7-;/m1./s1
• Code InChI: InChIKey=HHMABTMGEFVHQT-BZUDZRPRSA-N
• SMILES: Cl.N[C@@H]1C[C@H](OCCO)[C@@H](O)[C@H]1O