5-Amino-1-methyl-4-nitroimidazole

CAS : 4531-54-8

Ref. TR-A617020

Informations sur le produit

• Nom: 5-Amino-1-methyl-4-nitroimidazole
• Synonymes: 1H-Imidazol-5-amine, 1-methyl-4-nitro-, Imidazole, 5-amino-1-methyl-4-nitro- (7CI,8CI), 1-Methyl-4-nitro-1H-imidazol-5-amine, NSC 400013, 1H-Imidazol-5-amine, 1-methyl-4-nitro-, 3-Methyl-5-nitro-3H-imidazol-4-ylamine, 3-Methyl-5-nitroimidazol-4-amine, Imidazole, 5-amino-1-methyl-4-nitro-

Description

Applications 5-Amino-1-methyl-4-nitroimidazole is a moiety of Azathioprine (A803350); an immunosuppressive antimetabolite that is also active as a disease modifying antirheumatic drug (DMARD).
References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 142.12
• Formule: C₄H₆N₄O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C4H6N4O2/c1-7-2-6-4(3(7)5)8(9)10/h2H,5H2,1H3
• SMILES: Cn1cnc([N+](=O)[O-])c1N