(5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

CAS : 101328-84-1

Ref. TR-A622634

Informations sur le produit

• Nom: (5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone
• Synonymes: (4S)-3-(4-aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one

Description

Applications (5S)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone is an intermediate in the synthesis of Dextrosimendan (D299550), an isomer and impurity of Levosimendan (L378000), a bioactive enantiomer of Simendan (S466000). Levosimendan is a positive inotropic agent with vasodilating activity.
References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 203.24
• Formule: C₁₁H₁₃N₃O
• Couleur/Forme: Neat
• InChI: InChI=1S/C11H13N3O/c1-7-6-10(15)13-14-11(7)8-2-4-9(12)5-3-8/h2-5,7H,6,12H2,1H3,(H,13,15)/t7-/m0/s1
• Code InChI: InChIKey=GDMRFHZLKNYRRO-ZETCQYMHSA-N
• SMILES: C[C@H]1CC(=O)NN=C1c1ccc(N)cc1