4'-[(o-Aminophenyl)sulfonyl]-acetanilide

CAS : 18514-07-3

Ref. TR-A626850

Informations sur le produit

• Nom: 4'-[(o-Aminophenyl)sulfonyl]-acetanilide
• Synonymes: N-[4-[(2-Aminophenyl)sulfonyl]phenyl]-acetamide, Dapsone Impurity

Description

Applications 4'-[(o-Aminophenyl)sulfonyl]-acetanilide is an impurity of dapsone (D193250). Dapsone is an antibacterial used in the treatment of dermatitis herpetiformis.
References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 164.156
• Formule: C₁₄H₁₄N₂O₃S
• Couleur/Forme: Neat
• InChI: InChI=1S/C14H14N2O3S/c1-10(17)16-11-6-8-12(9-7-11)20(18,19)14-5-3-2-4-13(14)15/h2-9H,15H2,1H3,(H,16,17)
• Code InChI: InChIKey=SHZGCJCMOBCMKK-BWQZKHCESA-N
• SMILES: CC1O[C@@H](O)C(O)C(O)[C@H]1O