9-Amino-1,2,3,4-tetrahydroacridin-1-ol Maleate

CAS : 118909-22-1

Ref. TR-A629900

Informations sur le produit

• Nom: 9-Amino-1,2,3,4-tetrahydroacridin-1-ol Maleate
• Synonymes: 9-amino-1,2,3,4-tetrahydroacridin-1-ol;(Z)-but-2-enedioic acid, (+-)-9-Amino-1,2,3,4-tetrahydro-1-acridinol maleate (1:1) (salt), 1-Acridinol, 9-amino-1,2,3,4-tetrahydro-, (+-)-, (Z)-2-butenedioate (1:1) (salt), 1-Acridinol, 9-amino-1,2,3,4-tetrahydro-, (2Z)-2-butenedioate (1:1), 1-Acridinol, 9-amino-1,2,3,4-tetrahydro-, (2Z)-2-butenedioate (1:1) (salt), Hp 029, Mentane, P 83-6029A, Unii-Yy1Jw04Jcb, Velnacrine hydrogen maleate, Velnacrine maleate

Description

Applications A potential Alzheimer's Disease therapeutic of low toxicity. Exhibits biochemical and pharmacological profile similar to THA except that it is far less toxic and without measurable liver toxicity in humans.
References Alon, R., et al.: J. Cell Biol., 128, 1243 (1995), Min, W., et al.: J .Immunol., 159, 3508 (1997), Lum, A., et al.: J. Biol. Chem., 277, 20660 (2002), Carvalho, F., et al.: J. Appl. Toxicol., 24, 419 (2004),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 330.34
• Formule: C₁₃H₁₄N₂O·C₄H₄O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C13H14N2O.C4H4O4/c14-13-8-4-1-2-5-9(8)15-10-6-3-7-11(16)12(10)13;5-3(6)1-2-4(7)8/h1-2,4-5,11,16H,3,6-7H2,(H2,14,15);1-2H,(H,5,6)(H,7,8)/b;2-1-
• Code InChI: InChIKey=NEEKVKZFYBQFGT-BTJKTKAUSA-N
• SMILES: Nc1c2c(nc3ccccc13)CCCC2O.O=C(O)/C=C\C(=O)O