4-[[4-[4-(4-Aminophenyl)-1-piperazinyl]phenoxy]methyl]-2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol

CAS : 184378-04-9

Ref. TR-A632254

Informations sur le produit

• Nom: 4-[[4-[4-(4-Aminophenyl)-1-piperazinyl]phenoxy]methyl]-2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
• Synonymes: POSA BB4, 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)aniline

Description

Applications 4-[[4-[4-(4-Aminophenyl)-1-piperazinyl]phenoxy]methyl]-2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol is an impurity of (S)-Citalopram (C505005). (S)-Citalopram is an inhibitor of serotonin (5-HT) uptake. Antidepressant.
References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977); Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000); Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 546.611
• Formule: C₃₀H₃₂F₂N₆O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C30H32F2N6O2/c31-23-1-10-28(29(32)15-23)30(19-38-21-34-20-35-38)16-22(18-40-30)17-39-27-8-6-26(7-9-27)37-13-11-36(12-14-37)25-4-2-24(33)3-5-25/h1-10,15,20-22H,11-14,16-19,33H2/t22-,30+/m1/s1
• Code InChI: InChIKey=BKLNBLKPZPFLRD-RCRUUEGKSA-N
• SMILES: Nc1ccc(N2CCN(c3ccc(OC[C@@H]4CO[C@@](Cn5cncn5)(c5ccc(F)cc5F)C4)cc3)CC2)cc1