Androst-4-ene-3,17-dione-2,2,4,6,6,16,16-d7

CAS : 67034-85-9

Ref. TR-A637942

Informations sur le produit

• Nom: Androst-4-ene-3,17-dione-2,2,4,6,6,16,16-d7
• Synonymes: (8R,9S,10R,13S,14S)-2,2,4,6,6,16,16-heptadeuterio-10,13-dimethyl-1,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthrene-3,17-dione
• Marque: TRC

Description

Applications Androst-4-ene-3,17-dione-2,2,4,6,6,16,16-d7 is an intermediate in the synthesis of Dehydroepiandrosterone-d5 which is the labeled analogue of Dehydro Epiandrosterone (D229585). Dehydro Epiandrosterone is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.
References Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977), Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994), Ebeling, P., et al.: Lancet, 343, 1479 (1994),

Propriétés chimiques

• Masse moléculaire: 293.46
• Formule: C₁₉D₇H₁₉O₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1/i3D2,6D2,7D2,11D
• Code InChI: InChIKey=PNLUGRYDUHRLOF-UHFFFAOYSA-N
• SMILES: C=CN(C)C(C)=O