3,4,6,7-Tetrahydro-1,4-benzoxazine-rearranged Amlodipine

CAS : 496024-43-2

Ref. TR-A639938

Informations sur le produit

• Nom: 3,4,6,7-Tetrahydro-1,4-benzoxazine-rearranged Amlodipine
• Synonymes: 2H-1,4-Benzoxazine-5,7-dicarboxylic acid, 6-(2-chlorophenyl)-3,4,6,7-tetrahydro-8-methyl-, 5-ethyl 7-methyl ester, 5-Ethyl 7-methyl 6-(2-chlorophenyl)-3,4,6,7-tetrahydro-8-methyl-2H-1,4-benzoxazine-5,7-dicarboxylate, 5-Ethyl 7-methyl 6-(2-chlorophenyl)-8-methyl-3,4,6,7-tetrahydro-2H-1,4-benzo[b][1,4]oxazine-5,7-dicarboxylate
• Marque: TRC
• Description: Applications Amlodipine Besylate Impurity is an impurity of Amlodipine (A633500), a dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive.References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996)

Propriétés chimiques

• Masse moléculaire: 391.85
• Formule: C₂₀H₂₂ClNO₅
• Couleur/Forme: Off-White
• InChI: InChI=1S/C20H22ClNO5/c1-4-26-20(24)16-15(12-7-5-6-8-13(12)21)14(19(23)25-3)11(2)18-17(16)22-9-10-27-18/h5-8,14-15,22H,4,9-10H2,1-3H3
• Code InChI: InChIKey=ZTKBXGUJDFQQPS-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C2NCCOC2=C(C)C(C(=O)OC)C1c1ccccc1Cl