Apafant

CAS : 105219-56-5

Ref. TR-A726100

Informations sur le produit

• Nom: Apafant
• Synonymes: 4-[3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-oxopropyl]morpholine, WEB 2086BS, WEB 2086, 1-Propanone, 3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-, 105219-56-5, 3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-1-propanone, 3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(morpholin-4-yl)propan-1-one, 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, morpholine deriv., Morpholine, 4-[3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-oxopropyl]-, Web 2086, Web 2086Bs

Description

Applications Platelet activating factor (PAF) antagonist.
References Casals-Stenzel, J., et al.: J. Pharmacol. Exp. Ther., 241, 974 (1987), Adamus, W.S., et al.: Clin. Pharmacol. Ther., 47, 456 (1990), Brecht, H.M., et al.: Arzneim.-Forsch., 41, 51 (1991),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 455.96
• Formule: C₂₂H₂₂ClN₅O₂S
• Couleur/Forme: White to Light Yellow Solid
• InChI: InChI=1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3
• Code InChI: InChIKey=JGPJQFOROWSRRS-UHFFFAOYSA-N
• SMILES: Cc1nnc2n1-c1sc(CCC(=O)N3CCOCC3)cc1C(c1ccccc1Cl)=NC2