Atorvastatin-Amlodipine Adduct

CAS : 425408-16-8

Ref. TR-A791695

Informations sur le produit

• Nom: Atorvastatin-Amlodipine Adduct
• Synonymes: 3-Ethyl 5-Methyl 4-(2-Chlorophenyl)-2-[[2-[[(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
• CAS: 425408-16-8

Description

Applications Atorvastatin-Amlodipine Adduct is an an amlodipine (A633495) / atorvastatin amide prodrug.
References Crook, Robert J., et al.: Eur. Pat. Appl., EP 1205477 A1 20020515 (2002)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 949.5
• Formule: C₅₃H₅₈ClFN₄O₉
• Couleur/Forme: Neat
• InChI: InChI=1S/C53H58ClFN4O9/c1-6-68-53(65)47-42(57-33(4)44(52(64)66-5)46(47)40-19-13-14-20-41(40)54)31-67-28-26-56-43(62)30-39(61)29-38(60)25-27-59-49(32(2)3)48(51(63)58-37-17-11-8-12-18-37)45(34-15-9-7-10-16-34)50(59)35-21-23-36(55)24-22-35/h7-24,32,38-39,46,57,60-61H,6,25-31H2,1-5H3,(H,56,62)(H,58,63)/t38-,39-,46?/m1/s1
• Code InChI: InChIKey=MCXKYSIVTQMUGD-CMOYLYLHSA-N
• SMILES: CCOC(=O)C1=C(COCCNC(=O)C[C@H](O)C[C@H](O)CCn2c(-c3ccc(F)cc3)c(-c3ccccc3)c(C(=O)Nc3ccccc3)c2C(C)C)NC(C)=C(C(=O)OC)C1c1ccccc1Cl