AZD-9291 Mesylate

CAS : 1421373-66-1

Ref. TR-A808205

Informations sur le produit

• Nom: AZD-9291 Mesylate
• Synonymes: 2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-, methanesulfonate (1:1), Osimertinib mesylate, Osimertinib mesilate, 2-Propenamide, N-[2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-, methanesulfonate (1:1), N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1), AZD-9291 mesylate, AZD 9291 mesylate

Description

Applications AZD-9291 Mesylate is a potent and selective epidermal growth factor receptor (EGFR) inhibitor.
References Finlay, M.; et al.: J. Med. Chem., 57, 8249 (2014)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 595.71
• Formule: C₂₈H₃₃N₇O₂·CH₄O₃S
• Couleur/Forme: Neat
• InChI: InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3)32-28-29-13-12-21(31-28)20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2-6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)
• Code InChI: InChIKey=FUKSNUHSJBTCFJ-UHFFFAOYSA-N
• SMILES: C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C.CS(=O)(=O)O