Azoniaspironortropanol-d8 Chloride

CAS : 3464-71-9

Ref. TR-A965127

Informations sur le produit

• Nom: Azoniaspironortropanol-d8 Chloride
• Synonymes: (1R,5S)-2',2',3',3',4',4',5',5'-octadeuteriospiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-ol;chloride, Spiro[8-azoniabicyclo[3.2.1]octane-8,1′-pyrrolidinium], 3-hydroxy-, chloride (1:1), (1α,3β,5α)-, 3-Hydroxyspiro[nortropane-8,1′-pyrrolidinium] chloride, 3α-Hydroxynortropane-8-spiro-1′-pyrrolidinium chloride, Spiro[8-azoniabicyclo[3.2.1]octane-8,1′-pyrrolidinium], 3-hydroxy-, chloride, (1α,3β,5α)-, Spiro[1αH,5αH-nortropane-8,1′-pyrrolidinium], 3α-hydroxy-, chloride

Description

Applications Azoniaspironortropanol-d8 Chloride is the labeled analogue of Azoniaspironortropanol Chloride (A965125), an intermediate used for the synthesis of Trospium Chloride (T892800), an Antispasmodic, used in treatment of urinary incontinence.
References Antweiler, H., et al.: Arzneim.-Forsch., 16, 1581 (1966); Lux, G., et al.: Fortschr. Med., 96, 2113 (1978); Madersbacher, H., et al.: Br. J. Urol., 75, 452 (1995); Zinner, N.R., et al.: Expert Opin. Pharmacother., 6, 1409 (2005)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 225.785
• Formule: C₁₁D₈H₁₂NO·Cl
• Couleur/Forme: Neat
• InChI: InChI=1S/C11H20NO.ClH/c13-11-7-9-3-4-10(8-11)12(9)5-1-2-6-12;/h9-11,13H,1-8H2;1H/q+1;/p-1/t9-,10+,11+;/i1D2,2D2,5D2,6D2
• SMILES: [2H]C1([2H])C([2H])([2H])C([2H])([2H])[N+]2([C@H]3CC[C@@H]2C[C@H](O)C3)C1([2H])[2H].[Cl-]