Benznidazole

CAS : 22994-85-0

Ref. TR-B197925

Informations sur le produit

• Nom: Benznidazole
• Synonymes: N-benzyl-2-(2-nitroimidazol-1-yl)acetamide, 1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)-, 2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide, Benznidazol, Benzonidazol, Benzonidazole, Imidazole-1-acetamide, N-benzyl-2-nitro-, N-Benzyl-2-nitroimidazol-1-yl-acetamide, N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide, N-benzyl-2-nitro-1H-imidazole-1-acetamide, NSC 299972, Radanil, Ro 07-1051, Ro 71051, Rochagan

Description

Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.
References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 260.25
• Formule: C₁₂H₁₂N₄O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C12H12N4O3/c17-11(14-8-10-4-2-1-3-5-10)9-15-7-6-13-12(15)16(18)19/h1-7H,8-9H2,(H,14,17)
• SMILES: O=C(Cn1ccnc1[N+](=O)[O-])NCc1ccccc1