2-[(1-Benzyl-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile

CAS : 1144853-53-1

Ref. TR-B285735

Informations sur le produit

• Nom: 2-[(1-Benzyl-2-oxo-5-(thiomorpholinosulfonyl)indolin-3-ylidene]malononitrile
• Synonymes: 2-[1,2-Dihydro-2-oxo-1-(phenylmethyl)-5-(4-thiomorpholinylsulfonyl)-3H-indol-3-ylidene]propanedinitrile
• Marque: TRC

Description

Applications Isatin sulfonamide analog as Caspase-3 inhibitors.
References Thompson, C., et al.: Science, 267, 1456 (1995), Chu, W., et al.: J. Med. Chem., 48, 7637 (2005), Jana, S., et al.: Curr. Med. Chem., 14, 2369 (2007), Schoenberger, J., et al.: Curr. Med. Chem., 15, 187 (2008),

Propriétés chimiques

• Masse moléculaire: 450.53
• Formule: C₂₂H₁₈N₄O₃S₂
• Couleur/Forme: Neat
• InChI: InChI=1S/C22H18N4O3S2/c23-13-17(14-24)21-19-12-18(31(28,29)25-8-10-30-11-9-25)6-7-20(19)26(22(21)27)15-16-4-2-1-3-5-16/h1-7,12H,8-11,15H2
• SMILES: N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCSCC3)cc21