(Z)-Betamethasone-∆17,20 21-Aldehyde

CAS : 52647-06-0

Ref. TR-B327175

Informations sur le produit

• Nom: (Z)-Betamethasone-∆17,20 21-Aldehyde
• Synonymes: (Z)-2-((8S,9R,10S,11S,13S,14S,16S)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-3,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-17H-cyclopenta[a]phenanthren-17-ylidene)-2-hydroxyacetaldehyde, (Z)-9-Fluoro-11ß,20-dihydroxy-16ß-methylpregna-1,4,17(20)-triene-3,21-dione, (11ß,16ß,17Z)-9-Fluoro-11,20-dihydroxy-16-methyl-3-oxopregna-1,4,17(20)-trien-21-al, Betamethasone-(Z)-enolaldehyde, (Z)-9-Fluoro-11ß,20-dihydroxy-16ß-methylpregna-1,4,17(20)-triene-3,21-dione

Description

Stability Hygroscopic
Applications (Z)-Betamethasone-∆17,20 21-Aldehyde is the Z isomer and degradation production of Betamethasone (B327000) in acid medium;Also, it is derived from Betamethasone Dipropionate (B327005), which is a glucocorticoid. Used as anti-inflammatory and antibacterial ointment for dermatosis.
References Hidaka, T., et al.: Yakugaku Zasshi, 100, 72-80 (1980); Dahlman-Ghozlan, K., et al.: Exp. Dermatol., 13, 65 (2004), Gounni Abdelilah, S., et al.: Clin. Immunol., 120, 220 (2006), Hertl, M., et al.: J. Clin. Invest., 116, 1159 (2006)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 374.44
• Formule: C₂₂H₂₇FO₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C22H27FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,11-12,15-16,18,26-27H,4-5,8,10H2,1-3H3/b19-17-/t12-,15-,16-,18-,20-,21-,22-/m0/s1
• Code InChI: InChIKey=TYYMPHSFTLTHRI-NIQJDLCESA-N
• SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)/C1=C(\O)C=O