Bimatoprost Acid

CAS : 38344-08-0

Ref. TR-B386820

Informations sur le produit

• Nom: Bimatoprost Acid
• Synonymes: 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, (5Z)-, 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-, (5Z)- (9CI), 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-, [1R-[1a(Z),2ß(1E,3S*),3a,5a]]-, (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic acid, (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(S,E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid, 17-Phenyl-18,19,20-trinor-PGF2a, 17-Phenyl-18,19,20-trinorprostaglandin F2a, PhXA 70, U 35687, U-35687, 17-Phenyl-18,19,20-trinorprostaglandin F2α, 17-Phenyl-18,19,20-trinorprostaglandin F2α, 5-Heptenoic acid, 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-, [1R-[1α(Z),2β(1E,3S*),3α,5α]]-, Bimatoprost acid, (5Z,13E,15S)-9α,11α,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-diene-1-oic acid, 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, (5Z)-, 17-Phenyltrinorprostagrandin F2α, (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-diene-1-oic acid, 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-, (5Z)-

Description

Applications Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost (B386820).Bimatoprost Acid is a metabolically stable analog of PGF2α (P838625) and is a potent agonist for the FP receptor.
References Balapure, A.K. et al.: Biochem. Pharmacol., 38, 2375 (1989); Hellberg, M.R. et al.: J. Ocular Pharmacol. Ther., 19, 97 (2003); Krishna, P.M. et al.: J. Pharm. res., 4, 2381 (2011);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 388.50
• Formule: C₂₃H₃₂O₅
• Couleur/Forme: White To Off-White
• InChI: InChI=1S/C23H32O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,14-15,18-22,24-26H,2,7,10-13,16H2,(H,27,28)/b6-1-,15-14+/t18-,19+,20+,21-,22+/m0/s1
• Code InChI: InChIKey=YFHHIZGZVLHBQZ-KDACTHKWSA-N
• SMILES: O=C(O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCc1ccccc1