Boc-D-4,4'-biphenylalanine

CAS : 128779-47-5

Ref. TR-B642900

Informations sur le produit

• Nom: Boc-D-4,4'-biphenylalanine
• Synonymes: (aR)-a-[[(1,1-Dimethylethoxy)carbonyl]amino]-[1,1'-biphenyl]-4-propanoic Acid, (R)-a-[[(1,1-Dimethylethoxy)carbonyl]amino]-[1,1'-biphenyl]-4-propanoic Acid, (R)-3-(Biphenyl-4-yl)-2-[(tert-butoxycarbonyl)amino]propionic Acid, Boc-D-4,4-Biphenylalanine, (2S)-3-biphenyl-4-yl-2-[(tert-butoxycarbonyl)amino]propanoic acid (non-preferred name), (2R)-3-biphenyl-4-yl-2-[(tert-butoxycarbonyl)amino]propanoic acid (non-preferred name), N-(tert-butoxycarbonyl)-beta-phenyl-D-phenylalanine, Boc-D-4-Phenylphenylalanine, (R)-3-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid
• CAS: 128779-47-5

Description

Applications Boc-D-4,4'-biphenylalanine is used as a reagent in the synthesis of pyrrolopyrimidine inhibitors of Akt as antitumor agents. Boc-D-4,4'-biphenylalanine is also used in the preparation of (-)-Bestatin-based inhibitors.
References Blake, J.F., et al.: Bioorg. Med. Chem. Lett., 20, 5607 (2010); Velmourougane, G., et al.: J. Med. Chem., 54, 1655 (2011)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 341.4
• Formule: C₂₀H₂₃NO₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H23NO4/c1-20(2,3)25-19(24)21-17(18(22)23)13-14-9-11-16(12-10-14)15-7-5-4-6-8-15/h4-12,17H,13H2,1-3H3,(H,21,24)(H,22,23)/t17-/m1/s1
• Code InChI: InChIKey=NBVVKAUSAGHTSU-QGZVFWFLSA-N
• SMILES: CC(C)(C)OC(=O)N[C@H](Cc1ccc(-c2ccccc2)cc1)C(=O)O