cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate

CAS : 61397-56-6

Ref. TR-B685405

Informations sur le produit

• Nom: cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate
• Synonymes: (2R,4R)-rel-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-methanol 4-Benzoate, 1,3-Dioxolane-4-methanol, 2-(bromomethyl)-2-(2,4-dichlorophenyl)-, benzoate, (2R,4R)-rel- (9CI), 1,3-Dioxolane-4-methanol, 2-(bromomethyl)-2-(2,4-dichlorophenyl)-, benzoate, cis-, (2R,4R)-rel-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-methanol benzoate, [(2RS,4RS)-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate
• Marque: TRC

Description

Applications cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate is an intermediate in the preparation of antifungal agents such as Ketoconazole (K186000), Itraconazole (I937500) and Terconazole.
References Heeres, J. et al.: J. Med. Chem., 26, 611 (1983);

Propriétés chimiques

• Masse moléculaire: 446.12
• Formule: C₁₈H₁₅BrCl₂O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C18H15BrCl2O4/c19-11-18(15-7-6-13(20)8-16(15)21)24-10-14(25-18)9-23-17(22)12-4-2-1-3-5-12/h1-8,14H,9-11H2/t14-,18-/m0/s1
• Code InChI: InChIKey=OXUPOIXSQGXRGF-KSSFIOAISA-N
• SMILES: O=C(OC[C@H]1CO[C@](CBr)(c2ccc(Cl)cc2Cl)O1)c1ccccc1