Bufrolin

CAS : 54867-56-0

Ref. TR-B689405

Informations sur le produit

• Nom: Bufrolin
• Synonymes: 6-butyl-4,10-dioxo-1,7-dihydro-1,7-phenanthroline-2,8-dicarboxylic acid, Bufrolin [INN:BAN], 6-Butyl-1,4,7,10-tetrahydro-4,10-dioxo-1,7-phenanthroline-2,8-dicarbonsaeure, Bufroline, Bufroline [INN-French], Bufrolino, Bufrolino [INN-Spanish], Bufrolinum, Bufrolinum [INN-Latin], Unii-46C1Px266N, 6-Butyl-1,4,7,10-tetrahydro-4,10-dioxo-1,7-phenanthroline-2,8-dicarboxylic acid, 6-Butyl-4,10-Dioxo-1,4,7,10-Tetrahydro-1,7-Phenanthroline-2,8-Dicarboxylic Acid

Description

Applications Bufrolin is an analog of Sodium Cromoglycate (C815000). It is a mast cell stabilizer drug and is shown to display agonism at either human or rat G protein-coupled receptor GPR35.
References Church, Martin K., et al.: Int. Arch. Aller. A. Imm., 66, 281-2 (1981); MacKenzie Amanda E., et al.: Mol. Pharmacol., 85(1), 91-104 (2014)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 356.33
• Formule: C₁₈H₁₆N₂O₆
• Couleur/Forme: Neat
• InChI: InChI=1S/C18H16N2O6/c1-2-3-4-8-5-9-12(21)6-10(17(23)24)20-16(9)14-13(22)7-11(18(25)26)19-15(8)14/h5-7H,2-4H2,1H3,(H,19,22)(H,20,21)(H,23,24)(H,25,26)
• Code InChI: InChIKey=BQVIONBNDNFCCP-UHFFFAOYSA-N
• SMILES: CCCCc1cc2c(=O)cc(C(=O)O)[nH]c2c2c(=O)cc(C(=O)O)[nH]c12