N-tert-Butyl Cimicoxib

CAS : 499777-85-4

Ref. TR-B807078

Informations sur le produit

• Nom: N-tert-Butyl Cimicoxib
• Synonymes: N-tert-butyl-4-[4-chloro-5-(3-fluoro-4-methoxyphenyl)imidazol-1-yl]benzenesulfonamide

Description

Applications N-tert-Butyl Cimicoxib is an intermediate in the synthesis of Cimicoxib (C441690). Cimicoxib is a long-acting COX-2 Inhibitor and is developed as a non-steroidal anti-inflammatory veterinary drug used to treat dogs with inflammation and pain associated with osteoarthritis.
References Zambre, A.P., et al.: J. Chem. Info. Model., 47, 635 (2007); Sorbera, I.A., et al.: Drugs. Future., 29, 325 (2004); Almansa, C., et al.: J. Med. Chem., 3463 (2003)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 437.915
• Formule: C₂₀H₂₁ClFN₃O₃S
• Couleur/Forme: Neat
• InChI: InChI=1S/C20H21ClFN3O3S/c1-20(2,3)24-29(26,27)15-8-6-14(7-9-15)25-12-23-19(21)18(25)13-5-10-17(28-4)16(22)11-13/h5-12,24H,1-4H3
• Code InChI: InChIKey=FRZYUVYOHGEOAJ-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2c(Cl)ncn2-c2ccc(S(=O)(=O)NC(C)(C)C)cc2)cc1F