Canertinib

CAS : 267243-28-7

Ref. TR-C175600

Informations sur le produit

• Nom: Canertinib
• Synonymes: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide, N-[4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide, 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-, 4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propyloxy]-6-[(vinylcarbonyl)amino]quinazoline, Canertinib base, Cl 1033, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[2-(morpholin-4-yl)ethoxy]quinazolin-6-yl}prop-2-enamide, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide

Description

Applications Antineoplastic; irreversible pan-erbB tyrosine kinase inhibitor used to treat cancer.
References Li, D., et al.: Oncogene, 27, 4702 (2008), Brown, A., et al.: Toxicol. Pathol., 36, 410 (2008), Chen, H., et al.: Chem. Biol. Drug Design, 71, 434 (2008),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 485.94
• Formule: C₂₄H₂₅ClFN₅O₃
• Couleur/Forme: Pale Yellow Solid
• InChI: InChI=1S/C17H17NO2.ClH/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;/h2-6,13,19-20H,7-9H2,1H3;1H/t13-;/m1./s1
• Code InChI: InChIKey=SKYZYDSNJIOXRL-BTQNPOSSSA-N
• SMILES: CN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3.Cl