Cariprazine

CAS : 839712-12-8

Ref. TR-C183490

Informations sur le produit

• Nom: Cariprazine
• Synonymes: Urea, N'-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethyl-, N'-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, RGH 188, [trans-4-[[2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl]carbamoyl]cyclohexan-1-yl]-N,N-dimethylamine, N′-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea, Rgh 188, Vraylar

Description

Applications Cariprazine is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
References (1) Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010)(2) Seneca, N. et al.: Psychopharmacology, 218, 579 (2011)(3) Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 427.41
• Formule: C₂₁H₃₂Cl₂N₄O
• Couleur/Forme: Off-White
• InChI: InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-
• Code InChI: InChIKey=KPWSJANDNDDRMB-QAQDUYKDSA-N
• SMILES: CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1