(S)-Carisbamate

CAS : 194085-75-1

Ref. TR-C183510

Informations sur le produit

• Nom: (S)-Carisbamate
• Synonymes: 1,2-Ethanediol, 1-(2-chlorophenyl)-, 2-carbamate, (1S)-, 1,2-Ethanediol, 1-(2-chlorophenyl)-, 2-carbamate, (S)-, Carisbamate, Comfyde, JNJ 10234094, RWJ 333369, YKP 509, (+)-(2S)-2-(2-chlorophenyl)-2-hydroxyethyl carbamate, 1,2-Ethanediol, 1-(2-chlorophenyl)-, 2-carbamate, (1S)-, 1,2-Ethanediol, 1-(2-chlorophenyl)-, 2-carbamate, (S)-, Carisbamate [USAN], Jnj-10234094, Rwj 333369, S-2-O-Carbamoyl-1-o-chlorophenyl-ethanol, Unii-P7725I9V3Z, Ykp-509

Description

Applications Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, and exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.
References Novak GP, et al. 2007. Neurotherapeutics. Jan;4(1):106-9Nau C, 2004. J Membr Biol. Sep 1;201(1):1-8Codd EE, 2008. Pain. Feb;134(3):254-62. Epub 2007 May 25

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 215.63
• Formule: C₉H₁₀ClNO₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C9H10ClNO3/c10-7-4-2-1-3-6(7)8(12)5-14-9(11)13/h1-4,8,12H,5H2,(H2,11,13)/t8-/m1/s1
• Code InChI: InChIKey=OLBWFRRUHYQABZ-MRVPVSSYSA-N
• SMILES: NC(=O)OC[C@@H](O)c1ccccc1Cl