C2 Ceramide

CAS : 3102-57-6

Ref. TR-C262500

Informations sur le produit

• Nom: C2 Ceramide
• Synonymes: N-[(E,2R,3S)-1,3-dihydroxyoctadec-4-en-2-yl]acetamide, Acetamide, N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, [R-[R*,S*-(E)]]-, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide, Acetamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, Acetamide, N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, (E)-D-erythro-, Acetamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-

Description

Stability Moisture Sensitive
Applications A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.
References Inoue, T., et al.: J. Biol. Chem., 284, 9566 (2009), Kang, J., et al.: Bioorg. Med. Chem., 17, 1498 (2009), Rath, G., et al.: Int. J. Biochem. Cell Biol., 41, 1165 (2009),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 341.53
• Formule: C₂₀H₃₉NO₃
• Couleur/Forme: Off White Powder
• InChI: InChI=1S/C20H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(24)19(17-22)21-18(2)23/h15-16,19-20,22,24H,3-14,17H2,1-2H3,(H,21,23)/b16-15+/t19-,20+/m1/s1
• Code InChI: InChIKey=BLTCBVOJNNKFKC-FOCLMDBBSA-N
• SMILES: CCCCCCCCCCCCCC=CC(O)C(CO)NC(C)=O