C6 Ceramide-13C2,d2

CAS : 124753-97-5

Ref. TR-C262602

Informations sur le produit

• Nom: C6 Ceramide-13C2,d2
• Synonymes: N-Hexanoy-D-sphingosine-13C2,d2, N-Caproyl-D-sphingosine-13C2,d2, Caproyl Ceramide-13C2,d2, Caproyl Ceramide, Ceramide C6, C6 Ceramide Of D-Erythro-C8-Sphingosine, C6-D-Erythro-Ceramide, C8 Sphingoid Base, D-Erythro-Sphingosine, N-Hexanoyl-, 06:0 Ceramide, N-(1,3-dihydroxyoctadec-4-en-2-yl)hexanamide

Description

Applications A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.
References Dobrowsky, R.T., et al.: J. Biol. Chem., 268, 15523 (1993), Raines, M.A., et al.: J. Biol. Chem., 268, 14572 (1993), Jarvis, W.D., et al.: Proc. Natl. Acad. Sci. USA, 91, 73 (1994),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 401.63
• Formule: C₂₂₁₃C₂H₄₅D₂NO₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C24H47NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h18-19,22-23,26-27H,3-17,20-21H2,1-2H3,(H,25,28)/b19-18+/t22-,23+/m0/s1/i21+1D2,22+1
• Code InChI: InChIKey=NPRJSFWNFTXXQC-NICJHGTRSA-N
• SMILES: [2H][13C]([2H])(O)[13C@H](NC(=O)CCCCC)[C@H](O)/C=C/CCCCCCCCCCCCC