Cetirizine Dihydrochloride

CAS : 83881-52-1

Ref. TR-C281100

Informations sur le produit

• Nom: Cetirizine Dihydrochloride
• Synonymes: Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, dihydrochloride (9CI), Alercet, Alerid, Alerlisin, Cesta, Cetirizine hydrochloride, Cetrine, Cetrizet, Cistamine, Formistin, Histazine, Nosemin, P 071, Reactine, Riztec, Ryzen, Sancotec, Selitex, Triz, UCB-P 071, Virlix, Zeran, Zirtec, Zirtek, Zirtin, Zyrlex, Zyrtec, Zyrzine, Cetiriz, Cetrak, Epirizine, Histazine-1, Tomazine, (2-{4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Ethoxy)Acetic Acid Dihydrochloride, 2-(2-[4-[(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl]ethoxy)acetic acid dihydrochloride, 2-(2-{4-[(4-Chlorophenyl)(phenyl)-methyl]piperazino}ethoxy)acetic acid dihydrochloride, Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2), Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, dihydrochloride, Cetirizine Hcl, Cetirizine Hydrochloride, Cetirizine dihydrochloride, Cetrizine Di-HCl, Cetrizine dihydrochloride, Ucb-P 071

Description

Applications A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
References De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 461.81
• Formule: C₂₁H₂₅ClN₂O₃ClH
• Couleur/Forme: White To Off-White
• InChI: InChI=1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
• Code InChI: InChIKey=PGLIUCLTXOYQMV-UHFFFAOYSA-N
• SMILES: Cl.Cl.O=C(O)COCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1