(±)-Cetirizine-d4 Dihydrochloride

CAS : 1219803-84-5

Ref. TR-C281103

Informations sur le produit

• Nom: (±)-Cetirizine-d4 Dihydrochloride
• Synonymes: [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy-d4]acetic Acid Dihydrochloride, Alercet-d4, Alerid-d4, Alerlisin-d4, Cesta-d4, Cetiriz-d4, Cetirizine-d4 Hydrochloride, Cetrak-d4, Cetrine-d4, Cetrizet-d4, Cistamine-d4, Epirizine-d4, Formistin-d4, Histazine-d4, Histazine-1-d4, Nosemin-d4, P 071-d4, Reactine-d4, Riztec-d4, Ryzen-d4, Sancotec-d4, Selitex-d4, Tomazine-d4, Triz-d4, UCB-P 071-d4, Virlix-d4, Zeran-d4, Zirtec-d4, Zirtek-d4, Zirtin-d4, Zyrlex-d4, Zyrtec-d4, Zyrzine-d4
• CAS: 1219803-84-5

Description

Applications (±)-Cetirizine-d4 Dihydrochloride is the labeled analogue of Cetirizine Dihydrochloride (C281100), a nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
References De Vos, C., et al.: Ann. Allergy, 59, 278 (1987); Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987); Fadel, R., et al.: Clin. Allergy, 17, 373 (1987); Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 465.83
• Formule: C₂₁H₂₁D₄ClN₂O₃• 2HCl
• Couleur/Forme: Neat
• InChI: InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)/i14D2,15D2
• Code InChI: InChIKey=ZKLPARSLTMPFCP-QZPARXMSSA-N
• SMILES: [2H]C([2H])(OCC(=O)O)C([2H])([2H])N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1