L-erythro-Chloramphenicol

CAS : 7384-89-6

Ref. TR-C325015

Informations sur le produit

• Nom: L-erythro-Chloramphenicol
• Synonymes: [R-(R*,S*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamide, L-erythro-(+)-2,2-Dichloro-N-[ß-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]-acetamide, L-erythro-(1R,2S)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol, L-erythro-2,2-Dichloro-N-[ß-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]acetamide, 2,2-Dichloro-N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide, <span class="text-smallcaps">L</span>-(+)-erythro-Chloramphenicol, <span class="text-smallcaps">L</span>-erythro-(1R,2S)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol, <span class="text-smallcaps">L</span>-erythro-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide, Acetamide, 2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]-, L-erythro-(+)- (8CI), Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, <span class="text-smallcaps">L</span>-erythro-(+)-, Acetamide,2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[R-(R*,S*)]-, L-(+)-erythro-Chloramphenicol, L-erythro-2,2-Dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-nitrophenethyl]acetamide

Description

Applications L-erythro-Chloramphenicol functions as a potent inhibitor of electron transport in the mitochondria in biological studies. The L-isomer can be identified from the other CAP-isomers through reversed phase and chiral liquid chromatography in combination with tandem mass spectrometric detection.
References Berendsen, B., et al.: Anal. Chim. Acta., 700, 78 (2011), Wilson, S.B., et al.: Biochim. Biophys. Acta., 292, 603 (1973)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 323.13
• Formule: C₁₁H₁₂Cl₂N₂O₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9+/m0/s1
• Code InChI: InChIKey=PQTOLHHWLUCKSB-UHFFFAOYSA-N
• SMILES: COC(=O)CN=C(c1ccccc1)c1ccccc1