(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile

CAS : 565452-98-4

Ref. TR-C363785

Informations sur le produit

• Nom: (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
• Synonymes: (2R)-1-(2-Chloroacetyl)-2-pyrrolidinecarbonitrile (ACI), 2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2R)- (9CI), 2-Pyrrolidinecarbonitrile 1-(2-chloroacetyl)-, (2R)-, 2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2R)- (ACI)
• Marque: TRC

Description

Applications (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.
References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008); Villhauer, E. B., et al.: J. Med. Chem., 46, 2774 (2003);

Propriétés chimiques

• Masse moléculaire: 172.61
• Formule: C₇H₉ClN₂O
• Couleur/Forme: Neat
• InChI: InChI=1S/C7H9ClN2O/c8-4-7(11)10-3-1-2-6(10)5-9/h6H,1-4H2/t6-/m1/s1
• SMILES: N#C[C@H]1CCCN1C(=O)CCl