2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine Dihydrochloride

CAS : 2512203-91-5

Ref. TR-C367113

Informations sur le produit

• Nom: 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine Dihydrochloride
• Synonymes: N-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-N,N',N'-trimethyl-1,3-propanediamine Dihydrochloride, N1-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-N1,N3,N3-trimethyl-1,3-propanediamine Dihydrochloride, Chlorpromazine Dihydrochloride Impurity B, Chlorpromazine Dihydrochloride EP Impurity B

Description

Applications 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine Dihydrochloride is an impurity of Chlorpromazine (C424750), which is used as an antiemetic; antipsychotic. 2-Chloro-10-[3-[[3-(dimethylamino)propyl]methylamino]propyl]phenothiazine is also used in the synthesis of novel phenothiazine compounds with antimalarial activity.
References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970); Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990); Kalkanidis, M., et. al.: Biochem. Pharmacol., 63, 833 (2002)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 462.91
• Formule: C₂₁H₂₈ClN₃S• 2HCl
• Couleur/Forme: Neat
• InChI: InChI=1S/C21H28ClN3S.2ClH/c1-23(2)12-6-13-24(3)14-7-15-25-18-8-4-5-9-20(18)26-21-11-10-17(22)16-19(21)25;;/h4-5,8-11,16H,6-7,12-15H2,1-3H3;2*1H
• Code InChI: InChIKey=TUQCMXWJPGAJBI-UHFFFAOYSA-N
• SMILES: CN(C)CCCN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc21