(2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone

CAS : 915095-87-3

Ref. TR-C371265

Informations sur le produit

• Nom: (2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone
• Synonymes: (2-Chloro-5-Iodophenyl)(4-(((3S)-Tetrahydro-3-Furanyl)Oxy)Phenyl)Methanone, (2-Chloro-5-iodophenyl)-[4-[(3S)-oxolan-3-yl]oxyphenyl]methanone, (2-chloro-5-iodophenyl)-{4-[(S)-(tetrahydrofuran-3-yl)oxy]-phenyl}-methanone, (S)-(2-Chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone, Methanone, (2-chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]-

Description

Applications (2-Chloro-5-iodophenyl)[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methanone is an intermediate of Empagliflozin (E521510) which is a potent and selective SGLT-2 inhibitor that improves glycaemic control syndrome in diabetic rats.
References Wang, X., et al.: Org. Lett., 16, 4090 (2014);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 428.65
• Formule: C₁₇H₁₄ClIO₃
• Couleur/Forme: Off-White To Beige
• InChI: InChI=1S/C17H14ClIO3/c18-16-6-3-12(19)9-15(16)17(20)11-1-4-13(5-2-11)22-14-7-8-21-10-14/h1-6,9,14H,7-8,10H2/t14-/m0/s1
• Code InChI: InChIKey=WBBJCIOCSVFCNI-AWEZNQCLSA-N
• SMILES: O=C(c1ccc(O[C@H]2CCOC2)cc1)c1cc(I)ccc1Cl