4-(4-Chlorophenyl)-2-pyrrolidinone

CAS : 22518-27-0

Ref. TR-C379450

Informations sur le produit

• Nom: 4-(4-Chlorophenyl)-2-pyrrolidinone
• Synonymes: 4-(p-Chlorophenyl)-2-pyrrolidinone, 4-(4-Chlorophenyl)-2-pyrrolidone, Baclofen Related Compound A, Baclofen Imp. A (EP), (+/-)-Baclofen lactam, Baclofen Related Compound A, Baclofen Impurity A,(4RS)-4-(4-Chlorophenyl)pyrrolidin-2-one (Baclofen Lactam), (RS)-4-amino-3-(4-chlorophenyl)butyric acid lactam, (±)-Baclofen lactam, 2-Pyrrolidinone, 4-(4-Chlorophenyl)-, 2-Pyrrolidinone, 4-(p-chlorophenyl)-, 4-(4-Chlorophenyl)pyrrolidin-2-one

Description

Impurity Baclofen EP Impurity A
Applications 4-(4-Chlorophenyl)-2-pyrrolidinone is used in the preparation of potential and selective antagonists of the α1A adrenergic receptor (1,2). It is an impurity of Baclofen (B108000), a specific GABA-B receptor agonist. Muscle relaxant (skeletal).
References (1) Whitlock, G. et al.: Bioorg. med. Chem. Lett., 19, 3118 (2009)(2) Brogden, R.N., et al.: Drugs, 8,1 (1974)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 195.65
• Formule: C₁₀H₁₀ClNO
• Couleur/Forme: White
• InChI: InChI=1S/C10H10ClNO/c11-9-3-1-7(2-4-9)8-5-10(13)12-6-8/h1-4,8H,5-6H2,(H,12,13)
• Code InChI: InChIKey=OVRPDYOZYMCTAK-UHFFFAOYSA-N
• SMILES: O=C1CC(c2ccc(Cl)cc2)CN1