Ethyl 7-Chloro-4-ethoxy-6-fluoro-3,4-dihydroquinoline-3-carboxylate

CAS : 125292-94-6

Ref. TR-C433260

Informations sur le produit

• Nom: Ethyl 7-Chloro-4-ethoxy-6-fluoro-3,4-dihydroquinoline-3-carboxylate
• Synonymes: Ethyl 7-Chloro-4-ethoxy-6-fluoroquinoline-3-carboxylate

Description

Applications Ethyl 7-Chloro-4-ethoxy-6-fluoro-3,4-dihydroquinoline-3-carboxylate is an intermediate in the synthesis of Norfloxacin (N681000), which is a Pefloxacin derivative as antibacterial. Fluorinated quinolone antibacterial. This compound is a contaminant of emerging concern (CECs).
References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980); Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981); Holmes, B., et al.: Drugs, 30, 482 (1985)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 297.71
• Formule: C₁₄H₁₃ClFNO₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C14H13ClFNO3/c1-3-19-13-8-5-11(16)10(15)6-12(8)17-7-9(13)14(18)20-4-2/h5-7H,3-4H2,1-2H3
• Code InChI: InChIKey=BXQQSVJCMMSJSK-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cnc2cc(Cl)c(F)cc2c1OCC