Cinacalcet

CAS : 226256-56-0

Ref. TR-C441790

Informations sur le produit

• Nom: Cinacalcet
• Synonymes: 1-Naphthalenemethanamine, a-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, (aR)-, (aR)-a-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, AMG 073, N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine, (αR)-α-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine, 1-Naphthalenemethanamine, α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, (αR)-, Amg 073, Cinacalcel, N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine, N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine, N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride (1:1), Parareg

Description

Applications Cinacalcet is the first calcimimetic drug approved by the United States Food and Drug Administration for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease.
References Block, G, et al.: Am. J. Kidney Dis., 35, 1226 (2000), Moe, S., et al.: Am. J. Nephrol., 23, 369 (2003), Block, G., et al.: J. Am. Soc. Nephrol., 15, 2208 (2004).

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 357.41
• Formule: C₂₂H₂₂F₃N
• Couleur/Forme: Neat
• InChI: InChI=1S/C22H22F3N/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3/t16-/m1/s1
• Code InChI: InChIKey=VDHAWDNDOKGFTD-MRXNPFEDSA-N
• SMILES: C[C@@H](NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12