Cinitapride

CAS : 66564-14-5

Ref. TR-C441990

Informations sur le produit

• Nom: Cinitapride
• Synonymes: 4-Amino-N-[1-(3-cyclohexen-1-ylmethyl)-4-piperidinyl]-2-ethoxy-5-nitrobenzamide, 4-Amino-N-(1-(3-cyclohexen-1-ylmethyl)-4-piperidyl)-2-ethoxy-5-nitrobenzamide, 4-amino-N-[1-(cyclohex-3-en-1-ylmethyl)piperidin-4-yl]-2-ethoxy-5-nitrobenzamide, Benzamide, 4-amino-N-[1-(3-cyclohexen-1-ylmethyl)-4-piperidinyl]-2-ethoxy-5-nitro-, Cinitaprida, Cinitaprida [INN-Spanish], Cinitapride [INN], Cinitapridum, Cinitapridum [INN-Latin], Unii-R8I97I2L24

Description

Applications A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors (1,2,3).
References (1) Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997)(2) Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007)(3) Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 402.49
• Formule: C₂₁H₃₀N₄O₄
• Couleur/Forme: Neat
• InChI: InChI=1S/C21H30N4O4/c1-2-29-20-13-18(22)19(25(27)28)12-17(20)21(26)23-16-8-10-24(11-9-16)14-15-6-4-3-5-7-15/h3-4,12-13,15-16H,2,5-11,14,22H2,1H3,(H,23,26)
• SMILES: CCOc1cc(N)c([N+](=O)[O-])cc1C(=O)NC1CCN(CC2CC=CCC2)CC1