Clindamycin 2-Phosphate

CAS : 24729-96-2

Ref. TR-C580005

Informations sur le produit

• Nom: Clindamycin 2-Phosphate
• Synonymes: Clindamycin Phosphate, 7(S)-Chloro-7-deoxylincomycin 2-phosphate, Cleocin T, Cleocin phosphate, Clinadac, Clindac, Clindagel, Clindesse, Clindets, Dalacin P, Dalacin T, NSC 618653, U 28508, L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-(dihydrogen phosphate), L-threo-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, 2-(dihydrogen phosphate), trans- alpha-, L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-(dihydrogen phosphate), (2S-trans)-, Methyl 7-chloro-6,7,8-trideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside 2-(dihydrogen phosphate), <span class="text-smallcaps">L</smallcap>-threo-<smallcap>D</smallcap>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-<smallcap>L</span>-2-pyrrolidinecarboxamido)-1-thio-, 2-(dihydrogen phosphate), trans- α-, <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-(dihydrogen phosphate), (2S-trans)-, <span class="text-smallcaps">L</smallcap>-threo-α-<smallcap>D</span>-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-(dihydrogen phosphate), Clindamycin 2-phosphate, Methyl 7-Chloro-6,7,8-Trideoxy-6-(1-Methyl-Trans-4-Propyl-L-2-Pyrrolidinecarboxamido)-1-Thio-L-Threo-Alpha-D-Galacto-Octopyranoside 2-(Dihydrogen Phosphate), Methyl 7-chloro-6,7,8-trideoxy-6-trans-(1-methyl-4-propyl-<span class="text-smallcaps">L</smallcap>-2-pyrrolidinecarboxamido)-1-thio-<smallcap>L</smallcap>-threo-α-<smallcap>D</span>-galacto-octopyranoside 2-(dihydrogen phosphate), [(2R,3R,4S,5R,6R)-6-[2-chloro-1-[[(2S,4R)-1-methyl-4-propyl-pyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyl-tetrahydropyran-3-yl] dihydrogen phosphate, methyl 7-chloro-6,7,8-trideoxy-6-[(1-methyl-4-propylprolyl)amino]-2-O-phosphono-1-thiooctopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-2-O-phosphono-1-thio-L-threo-alpha-D-galacto-octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-2-O-phosphono-1-thiooctopyranoside, L-threo-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, 2-(dihydrogen phosphate), trans- α-, L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, 2-(dihydrogen phosphate), L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, 2-(dihydrogen phosphate), (2S-trans)-, Methyl 7-chloro-6,7,8-trideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate)

Description

Applications A highly water soluble Clindamycin prodrug.
References Ozensoy, O., et al.: J. Enz. Inhibit. Med. Chem., 23, 579 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Dubina, M., et al.: Arch. Dermatol., 145, 1027 (2009),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 504.96
• Formule: C₁₈H₃₄ClN₂O₈PS
• Couleur/Forme: White
• InChI: InChI=1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12+,13+,14-,15+,16+,18+/m0/s1
• Code InChI: InChIKey=UFUVLHLTWXBHGZ-GHGYQPCPSA-N
• SMILES: CCC[C@H]1C[C@H](C(=O)N[C@@H](C(C)Cl)[C@@H]2O[C@@H](SC)[C@@H](OP(=O)(O)O)[C@H](O)[C@@H]2O)N(C)C1