Clocortolone Acetate

CAS : 4258-85-9

Ref. TR-C583820

Informations sur le produit

• Nom: Clocortolone Acetate
• Synonymes: 9-Chloro-6a-fluoro-11ß,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-acetate, SH 818, 9-Chloro-6a-fluoro-11ß,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-Acetate, (6a,11ß,16a)-21-(Acetyloxy)-9-chloro-6-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, (6α,11β,16α)-21-(Acetyloxy)-9-chloro-6-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, 4258-85-9, 9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate, Clocortolone acetate, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-chloro-6-fluoro-11-hydroxy-16-methyl-, (6α,11β,16α)-, Pregna-1,4-diene-3,20-dione, 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methyl-, 21-acetate, Sh 818

Description

Applications Clocortolone Acetate is an intermediate in the synthesis of Clocortolone (C583800), an corticosteroid used in the treatment of skin inflammmation and other skin conditions arising for dermatoses.
References Rehm, K. et al.: Pharmaz. Zeit., 127, 888 (1982);

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 452.94
• Formule: C₂₄H₃₀ClFO₅
• Couleur/Forme: Neat
• InChI: InChI=1S/C24H30ClFO5/c1-12-7-15-16-9-18(26)17-8-14(28)5-6-23(17,4)24(16,25)20(30)10-22(15,3)21(12)19(29)11-31-13(2)27/h5-6,8,12,15-16,18,20-21,30H,7,9-11H2,1-4H3/t12-,15+,16+,18+,20+,21-,22+,23+,24+/m1/s1
• Code InChI: InChIKey=ARPLCFGLEYFDCN-CDACMRRYSA-N
• SMILES: CC(=O)OCC(=O)[C@H]1[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C