alpha-Clofarabine

CAS : 491594-60-6

Ref. TR-C586895

Informations sur le produit

• Nom: alpha-Clofarabine
• Synonymes: alpha-Clofarabine, 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-a-D-arabinofuranosyl)- (9CI, ACI), 2-Chloro-9-(2-deoxy-2-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine (ACI)

Description

Applications α-Clofarabine is a second generation purine nucleoside analog; antimetabolite that inhibits DNA synthesis and resists deamination by adenosine deaminase. Antineoplastic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gandhi, V., et al.: Clin. Cancer Res., 9, 6335 (2003); Kantarjian, H., et al.: Blood, 102, 2379 (2003); Faderl, S., et al.: Cancer, 103, 1985 (2005)

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 303.677
• Formule: C₁₀H₁₁ClFN₅O₃
• Couleur/Forme: Neat
• InChI: InChI=1S/C10H11ClFN5O3/c11-10-15-7(13)5-8(16-10)17(2-14-5)9-4(12)6(19)3(1-18)20-9/h2-4,6,9,18-19H,1H2,(H2,13,15,16)/t3-,4+,6-,9+/m1/s1
• Code InChI: InChIKey=LGAJOMLFGCSBFF-AUFPIVKFSA-N
• SMILES: COc1ccc2c(c1)c(CC(=O)NC1C(O)[C@@H](O)C(CO)O[C@H]1O)c(C)n2C(=O)c1ccc(Cl)cc1