Colistin Sulfate (Mixture of A and B compound)

CAS : 1264-72-8

Ref. TR-C641500

Informations sur le produit

• Nom: Colistin Sulfate (Mixture of A and B compound)
• Synonymes: Colomycin,Polymyxin E. Sulfate, Belcomycine, Belcomycin, Colimycin sulfate, Colistin Sulphate, Colistin, Sulfat (Salz), Colistin, sulfate (salt), Colistina, Sulfato (Sal), Colistine, Sulfate (Sel), Colomycin, Colomycin syrup, N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide, N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methyloctanamide sulfate (1:1), N-[3-Amino-1-[[1-[[3-Amino-1-[[6,9,18-Tris(2-Aminoethyl)-3-(1-Hydroxyethyl)-12,15-Bis(2-Methylpropyl)-2,5,8,11,14,17,20-Heptaoxo-1,4,7,10,13,16,19-Heptazacyclotricos-21-Yl]Carbamoyl]Propyl]Carbamoyl]-2-Hydroxy-Propyl]Carbamoyl]Propyl]-5-Methyl-Heptanamide Sulfate, Nipoxyme, Polymyxin E sulfate, Polymyxin E, sulfate (salt)

Description

Applications Cyclic polypeptide antibiotic produced by Bacillus polymyxa. Complex mixture of at least 30 components, primarily colistins A and B.[α]D= -65° (c= 1, Water) LOD: 3% DAB= α,γ-diaminobutyric acidHeavy Metals: 20ppm Colistin A R= (+)-6-methyloctanoylArsenic Content: 2ppm/g Colistin B R= 6-methylheptanoylSulfate: 16-18%Biological Potency (dry basis): 19600U/mg
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Suzuki, T., et al.: J. Biochem., 54, 25 (1963), Barnett, M., et al.: Br. J. Pharmacol. Chemother., 23, 552 (1964), Littlewood, J, M., et al.: Respir. Med., 94, 632 (2000), Li, J., et al.: Int. J. Antimicrob. Ag., 25, 11 (2005),

• Marque: TRC

Propriétés chimiques

• Masse moléculaire: 1169.46
• Formule: CompoundAC₅₃H₁₀₀N₁₆O₁₃·(H₂SO₄)CompoundBCH₉₈N₁₆O₁₃·(H₂SO₄)
• Couleur/Forme: White To Light Yellow
• InChI: InChI=1S/C53H100N16O13.H2O4S/c1-9-30(6)12-10-11-13-41(72)60-33(14-20-54)48(77)69-43(32(8)71)53(82)65-36(17-23-57)45(74)64-38-19-25-59-52(81)42(31(7)70)68-49(78)37(18-24-58)62-44(73)34(15-21-55)63-50(79)39(26-28(2)3)67-51(80)40(27-29(4)5)66-46(75)35(16-22-56)61-47(38)76;1-5(2,3)4/h28-40,42-43,70-71H,9-27,54-58H2,1-8H3,(H,59,81)(H,60,72)(H,61,76)(H,62,73)(H,63,79)(H,64,74)(H,65,82)(H,66,75)(H,67,80)(H,68,78)(H,69,77);(H2,1,2,3,4)/t30?,31-,32-,33+,34+,35+,36+,37+,38+,39+,40-,42+,43+;/m1./s1
• Code InChI: InChIKey=BAVYZALUXZFZLV-UHFFFAOYSA-N